SPES 2020 Deliverable D 1 . 2 . B - 6 SPES Metamodel
نویسندگان
چکیده
منابع مشابه
Anforderungen von Leitbranchen der deutschen Industrie an Variantenmanagement und Wiederverwendung und daraus resultierende Forschungsfragestellungen
Im Rahmen des bereits abgeschlossenen BMBF-Projektes SPES 2020 wurden mit dem SPES 2020 Modeling Framework verschiedene integrierte Konzepte, Techniken und Methoden zum durchgängigen Engineering von softwareintensiven eingebetteten Systemen entwickelt. Die aus Sicht der Industrie äußerst relevante Fragestellung nach einer möglichst bruchfreien Unterstützung des durchgängigen Variantenmanagement...
متن کاملPC-SPES: a potent inhibitor of nuclear factor-kappa B rescues mice from lipopolysaccharide-induced septic shock.
Septic shock is the most common cause of death in intensive care units, and no effective treatment is available at present. Lipopolysaccharide (LPS) is the primary mediator of Gram-negative sepsis by inducing the production of macrophage-derived proinflammatory cytokines, in which activation of nuclear factor-kappaB (NF-kappaB) plays an important role. PC-SPES is an eight-herb mixture active ag...
متن کاملThe effects of the October 1989 solar proton events on the stratosphere as computed using a threedimensional model
Very large solar proton events (SPEs) occurred from October 19-27, 1989. These SPEs are redicted to produce short-lived increases in HO x and ng-lived increases in NO x species, which both can lead to ozone destruction. December 1989 SBUV/2 measurements of upper stratospheric ozone show substantially more ozone depletion in the Northern than in the S0uthem Hemisphere ven thoug h the amount of H...
متن کاملClinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer.
BACKGROUND Herbal mixtures are popular alternatives to demonstrated therapies. PC-SPES, a commercially available combination of eight herbs, is used as a nonestrogenic treatment for cancer of the prostate. Since other herbal medicines have estrogenic effects in vitro, we tested the estrogenic activity of PC-SPES in yeast and mice and in men with prostate cancer. METHODS We measured the estrog...
متن کاملPC-SPES inhibits colon cancer growth in vitro and in vivo.
PC-SPES is a mixture of eight herbs with antiproliferative activity in prostate cancer cell lines and antitumor effects in animal models of prostate cancer. In addition, evidence of clinical efficacy in advanced prostate cancer has been reported. PC-SPES has also been shown to have antitumor activity against several other cancer cell lines including breast and neuroepithelial cancer, melanoma, ...
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